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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#12010 Breast

A 24-year-old woman notes a lump in her right breast for the past month. She is concerned because her sister was diagnosed with poorly differentiated "triple-negative" breast cancer at age 31. Ultrasonography of the breast shows a solid mass. Fine needle aspiration is attempted but no diagnostic cells are obtained. Mammography is performed and there is a single 1-cm density with small clustered calcifications in the right breast but no lesions of the opposite breast. Which of the following is the best course of action for this patient?

#12012 General

A 50-year-old man Shahid K. John has had increasing dyspnea for the past 3 years with associated occasional cough but little sputum production. Auscultation reveals that his lungs are hyper-resonant and is associated with expiratory wheeze. Pulmonary function tests reveal increased total lung capacity (TLC) and slightly increased FVC. There is decreased FEV1 and FEV1/FVC ratio also. ABG analysis reveals pH of 7.35, pO2 of 60 mm Hg and pCO2 of 48 mm Hg. What is the most likely diagnosis?

#12016 Cardiovascular system

A 58-year-old male presents with the sudden onset of excruciating pain. He describes the pain as beginning in the anterior chest, radiating to the back, and then moving downward into the abdomen. His blood pressure is found to be 160/110. Your differential diagnosis includes myocardial infarction; however, no changes are seen on ECG, and you consider this to be less of a possibility. You obtain an x-ray of this patient's abdomen and discover a "double-barrel" aoa. This abnormality most likely results from

#12043 Male Genital Tract

A 5-year-old boy has a history of recurrent urinary tract infections. Urine cultures have grown Escherichia coli, Proteus mirabilis, and Enterococcus. Physical examination now shows an abnormal constricted opening of the urethra on the ventral aspect of the penis, 1.5 cm from the tip of the glans penis. There also is a cryptorchid testis on the right and an inguinal hernia on the left. What term best describes the child's penile abnormality?

#12045 Chronic Lymphocytic Leukemia

A 68 year old woman was admitted with a history of weakness for two months. On examination, cervical lymph nodes were found enlarged and spleen was palpable 2 cm below the costal margin. Her hemoglobin was 10.5 g/dl, platelet count 27 x 109/L and total leukocyte count 40 x 109/L, which included 80 % mature lymphoid cells with coarse clumped chromatin. Bone marrow revealed a nodular lymphoid infiltrate. The peripheral blood lymphoid cells were positive for CD19, CD5, CD20 and CD23 and were negative for CD79B and FMC-7. The histopathological examination of the lymph node in this patient will most likely exhibit effacement of lymph node architecture by?

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