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Pathology General 359e082b

All of the following constitute familial cancer syndrome except -

A
Xeroderma-pigmentosum
B
Retinoblastoma
C
Neurofibromatosis
D
MEN-I
High-Yield Explanation
All are familial cancer syndromes. Xeroderma-pigmentosa is autosomal recessive, defective DNA repair syndrome. Other three are autosomal dominant inherited cancer syndrome. Amongst the given options best answer is a i.e. xeroderma pigmentosa because autosomal dominant inherited cancer syndromes are the most common type of genetically predisposed cancer.

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