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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#2105 Blood Vessels

A 6-year-old girl presents with a 2-week history of a skin rash over her buttocks and legs and joint pain. The parents report seeing blood in the urine. Physical examination reveals palpable purpuric skin lesions and markedly swollen knees. The results of laboratory studies reveal abnormally high erythrocyte sedimentation rate (30 mm/h), BUN of 25 mg/dL, and serum creatinine of 3 mg/dL. Urinalysis demonstrates RBCs and RBC casts. The stool guaiac test is positive. Biopsy of lesional skin reveals deposits of IgA in the walls of small blood vessels. Which of the following is the most likely diagnosis?

#2127 Blood

A 29-year-old, previously healthy man has had an enlarging nodular area on his arm for the past 8 months. On physical examination, there is an ulcerated, reddish violet, 3x7 cm lesion on his right forearm and nontender right axillary and left inguinal lymphadenopathy. A chest radiograph shows a 4-cm nodular left pleural mass. An abdominal CT scan shows a 5-cm right retroperitoneal mass. Biopsy of an inguinal node is performed, and microscopic examination shows large cells, some of which contain horseshoe-shaped nuclei and voluminous cytoplasm. The tumor cells cluster around venules and infiltrate sinuses. The patient goes into remission after chemotherapy. Which of the following markers is most likely to be positive in the tumor cells?

#2143 General

A 23-year-old male Subhas Raj presents to the medicine OPD with complaint of hematuria. There is no burning sensation during urination. He also has no history suggestive of respiratory tract infection. He gives a history of two of his relatives suffering from ‘some blood disease’. His coagulation studies are within normal limits. The hemoglobin electrophoresis shows the following: Hb A 60% and Hb S 40%. Which of the following is most likely true about this patient?

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