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Pathology Rheumatic Fever 722da2de

Anitshow's cells are seen in?

A
Rheumatic heart disease
B
Rheumatic arthritis
C
Bacterial endocarditis
D
Marantic endocarditis
High-Yield Explanation
Ans. is 'a' i.e., Rheumatic heart disease o Anitschkow (or Anichkov or catterpiller) cells are often cells associated with rheumatic heart disease. Anitschkow cells are enlarged macrophages found within granulomas (called Aschoff bodies) associated with the diseaseo Aschoff bodies (Aschoff nodules) are characteristic inflammatory lesions of acute rheumatic fever found in any of the three layers of heart, but mostly seen in myocardium (myocarditis)o They consist of foci of collagen surrounded by following cells : Lymphocytes (especially T-cells), plasma cells, aschoff giant cells, antischkow cells, histiocytes and fibroblasts. Neutrophils (polymorphonuclear cells) are characteristically absent.

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