MHC class III genes encode
High-Yield Explanation
*HLA class III contains genes for
• Complement components C2 and C4 of classical pathway (Not C3)
• Properdin factor B of alternate pathway
• Tumor necrosis factor: Alpha and Beta
• Heat shock protein 70
• Enzyme tyrosine hydroxylase
• Genes for MHC (also known as HLA) are located on short arm of chromosome 6.