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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#2523 Blood

A 33-year-old previously healthy man with persistent fever and heart murmur is diagnosed with infective endocarditis. He receives a high dosage of a cephalosporin antibiotic during the next 10 days. He now has increasing fatigue. On physical examination, he has tachycardia and scleral icterus. Laboratory studies show a hemoglobin level of 7.5 g/dL, platelet count of 261,000/ mm3, and total WBC count of 8300/ mm3. The direct Coombs test is positive. The peripheral blood smear shows reticulocytosis. Which of the following is the most likely cause of his anemia?

#2529 Kidney

A 38-year-old woman has been feeling lethargic for 4 months. On physical examination, she is afebrile, and her blood pressure is 140/90 mm Hg. Laboratory findings show the serum creatinine level is 5.8 mg/dL. C3 nephritic factor is present in serum, resulting in hypocomplementemia, and the ANA test result is negative. Urinalysis shows 2+ blood and 1+ protein. A renal biopsy is done; microscopic examination shows hypercellular glomeruli and prominent ribbonlike deposits along the lamina densa of the glomerular basement membrane. Which of the following forms of glomerulonephritis is most likely to be present in this patient?

#2533 Environment & Nutritional Pathology

A 55-year-old woman has been steadily gaining weight for the past 30 years. She underwent cholecystectomy for cholelithiasis 5 years ago. She does not smoke. She is now 164 cm (5 ft 4 in) tall and weighs 126 kg (BMI 47). On physical examination, she has a decreased range of motion with pain on movement of the knees. Laboratory studies show a serum glucose level of 176 mg/dL. This patient is at greatest risk of developing which of the following neoplasms?

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