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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#10503 Respiration

A 25-year-old woman has had progressive dyspnea and fatigue for the past 2 years. On physical examination, she has pedal edema, jugular venous distention, and hepatomegaly. Lung fields are clear on auscultation. Chest CT scan shows right heart enlargement. Cardiac catheterization is performed, and the pulmonary arterial pressure is increased, without gradients across the pulmonic valve, and no shunts are noted. A transbronchial biopsy is performed, and microscopic examination shows plexiform lesions. A mutation in a gene encoding for which of the following is most likely to cause her pulmonary disease?

#10517 Respiration

A 63-year-old man has had progressively worsening dyspnea over the past 10 years. He has noticed a 5-kg weight loss in the past 2 years. He has a chronic cough with minimal sputum production and no chest pain. On physical examination, he is afebrile and normotensive. A chest radiograph shows extensive interstitial disease. Pulmonary function tests show diminished DLCO, low FVC, and normal FEV1/FVC ratio. Increased exposure to which of the following pollutants is most likely to produce these findings?

#10542 C.V.S

A 26-year-old woman has had a fever for 5 days. On physical examination, her temperature is 38.2deg C, pulse is 100/min, respirations are 19/min, and blood pressure is 90/60 mm Hg. A cardiac murmur is heard on auscultation. Her sensorium is clouded, but there are no focal neurologic deficits. Laboratory findings include hemoglobin, 13.1 g/dL; platelet count, 233,300/ mm3; and WBC count, 19,200/ mm3. Blood cultures are positive for gram-positive bacteria. Urinalysis shows hematuria. An echocardiogram shows 1.5-cm vegetation on the mitral valve. Which of the following conditions is this patient most likely to develop?

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