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Pathology Breast 2b156324

Which of the following statements about Rheumatoid Factor is true ?

A
It is an IgM antibody directed against IgG
B
It is an IgG antibody directed against 1gM
C
It is more specific than Anti-CCP antibodies
D
It is positive in all cases of Juvenile Rheumatoid Ahritis
High-Yield Explanation
In rheumatoid ahritis it is suspected that antibodies plays a role in the disease. About80% of patients have serun IgM autoantibodies that bind to fc poion of their own self IgG. These antibodies are called rheumatoid factor. Ref :Robbins basic pathology 9th edition page no 784,green box=Pathogenesis

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