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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#7027 Central Nervous System

A 10-year-old boy has had persistent headaches for the past 3 months. On physical examination, he is afebrile. He has an ataxic gait and dysdiadochokinesia. CT scan of the head shows a 4-cm cystic mass in the right cerebellar hemisphere. Cerebral lateral ventricles are enlarged. A lumbar puncture is done. The CSF protein concentration is elevated, but the glucose level is normal. Neurosurgery is performed, and the mass is removed and sectioned. On gross examination, the mass is a cyst filled with gelatinous material. The cyst has a thin wall and a 1-cm mural nodule. Microscopically, the mass is composed of cells that stain positive for glial fibrillary acidic protein (GFAP) and have long, hair-like processes. What is the most likely diagnosis?

#7039 G.I.T.

A 44-year-old woman has had increasing abdominal distention for the past 6 weeks. On physical examination, there is an abdominal fluid wave, and bowel sounds are present. Paracentesis yields 1000 mL of slightly cloudy serous fluid. Cytologic examination of the fluid shows malignant cells consistent with adenocarcinoma. Molecular analysis of these cells shows an MSH2 gene mutation with microsatellite instability. Her medical history indicates that she has had no major medical illnesses and no surgical procedures. Her sister was diagnosed with endometrial cancer and her brother had carcinoma of the stomach. Which of the following conditions is the most likely cause of this patient's symptoms?

#7042 Blood

A 9-year-old, otherwise healthy girl has complained of pain in the right armpit for the past week. Examination shows tender, enlarged lymph nodes in the right axillary region. There are four linear and nearly healed abrasions over a 3x2 cm area of the distal ventral aspect of the right forearm and a single, 0.5-cm, slightly raised erythematous nodule over one of the abrasions. No other abnormalities are noted. Histologic examination of one of the lymph nodes shows stellate, necrotizing granulomas. The lymphadenopathy regresses over the next 2 months. Infection with which of the following is most likely to have produced these findings?

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