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Pathology Practice MCQs

Browse 15,526 high-yield clinical questions in Pathology. Includes detailed explanations, options, and topic tags.

#11366 Osteology

A 25-year-old man has had right knee pain with "popping and catching" for the past 2 years. On examination, there is a reduced range of motion at the right knee, but no tenderness or swelling. MR imaging reveals a 3-cm mass in the anterior joint space. Arthroscopic surgery with partial synovectomy is performed, and a nodular, encapsulated mass is removed. Microscopic examination of the mass shows synoviocyte-like tumor cells in a hyalinized stroma containing osteoclast-like giant cells and hemosiderin. An antagonist to which of the following growth factors is most useful in treating this lesion?

#11376 Genetics

A 30-year-old pregnant woman visits her obstetrician for prenatal care and eventual delivery. The patient volunteers that two of her three children had "yellow jaundice" at birth. Her youngest girl had been severely jaundiced and had been given two blood transfusions. Prenatal laboratory tests indicate that the mother is blood type O, Rh negative, whereas her husband is blood type A, Rh positive. The obstetrician samples amniotic fluid at 36 weeks of gestation to ascertain whether the fetus is mature enough for preterm delivery. Quantitative analysis of which of the following was most likely used as an indicator of fetal lung maturity?

#11385 Blood

A 22-year-old woman has experienced increasing dyspnea for the past 2 months. On physical examination, she is afebrile and normotensive. Inspiratory wheezes are noted on auscultation of the chest. A chest CT scan shows an 8x10 cm posterior mediastinal mass that impinges on the trachea and esophagus. A mediastinoscopy is performed, and a biopsy of the mass microscopically shows scattered large multinucleated cells, with prominent nucleoli that mark with CD15, and lymphocytes and macrophages separated by dense collagenous bands. Which of the following cells is most likely to be seen microscopically in this biopsy specimen?

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