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Microbiology Practice MCQs

Browse 11,603 high-yield clinical questions in Microbiology. Includes detailed explanations, options, and topic tags.

#3356 General

An 8 year old boy is taken to a pediatrician because of behavioral changes, mild intellectual deterioration, and "laziness." Over the next several months the boy develops increasing clumsiness and periodic, involuntary, jerky movements every 3 to 6 seconds. Visual deterioration is apparent upon visual field testing, and optic atrophy is evident on funduscopic examination. Cerebrospinal fluid studies do not show significant pleocytosis, but oligoclonal bands of IgG are present on CSF electrophoresis. The electroencephalogram shows periodic discharges that are synchronous with the periods of myoclonus. Computed tomography (CT) of the head shows low-density white matter lesions and cerebral atrophy. At the age of 10, the boy dies. Prior infection with which of the following agents was probably related to the patient's condition?

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#3370 Misc.

A mother brings her 1-month-old infant to the pediatrician. She says the baby is crying more than usual and is vomiting and does not want to eat. Meningitis is suspected, and a lumbar puncture is done, which shows the following results; Opening pressure = 240 mm H2O (normal = 100-200 mm H2O), WBC count: 1200/mm3, Protein: 200 mg/dL, Glucose: 30 mg/dL, Gram stain: gram-positive rods, W hich of the following organisms is most likely responsible for this infant's meningitis?

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#3375 Immunology

A 15-year-old male is rushed to the emergency room with a temperature of 103degF, severe headache, and stiff neck. Upon physical examination, a petechial rash is observed all over his body. Suspecting meningitis, the physician orders a lumbar puncture, revealing gram-negative diplococci (Neisseria meningitidis) on Gram stain. The physician wishes to use a more sensitive test to confirm this as the causative agent. Which of the following tests combines features of gel diffusion and immune-electrophoresis and is applicable only to negatively charged antigens?

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