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Pharmacology Central Nervous system fdeec4d8

All of the following statements about phenytoin are true except:

A
It follows Saturation kinetics
B
Anti-seizure activity closely resembles plasma concentration
C
Does not depress CNS
D
Cerebellar degeneration occurs on long-term administration
High-Yield Explanation
Phenytoin is not a CNS depressant; some sedation occurs at therapeutic doses, but this does not increase fuher with dose; rather toxic doses produce excitement and muscular rigidity. REF: ESSENTIALS OF MEDICAL PHARMACOLOGY KD TRIPATHI 8TH ED.

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