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Pharmacology General fce85320

Mechanism of action of azoles is

A
By altering membrane permeability
B
By blocking nucleic acid synthesis
C
By disrupting microtubules function
D
By inhibiting cell wall synthesis
High-Yield Explanation
According to the mechanism of action these can be classified as  Drugs altering membrane permeability  - Azoles  - Triazoles e.g. Fluconazole, itraconazole, voriconazole, terconazole, posaconazole. - Imidazoles e.g. Ketoconazole, miconazole, clotrimazole, econazole, butoconazole, oxiconazole, sertaconazole, sulconazole.  - Terbinafine, butenafine, naftifine. - Polyenes e.g. Amphotericin B, nystatin, hamycin  Drugs blocking nucleic acid synthesis e.g. Flucytosine  Drugs disrupting microtubule function e.g. Griseofulvin  Drugs inhibiting cell wall synthesis e.g. Caspofungin, nikkomycin.

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