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Pharmacology Central Nervous system fb1a4668

True statement regarding methadone are all except:

A
It is a long acting mue-receptor agonist
B
It is rapidly absorbed from the gastrointestinal tract and is detected in plasma 30minutes after oral administrations
C
The primary use of methadone is relief of chronic pain
D
The onset of analgesia is 30-60 minutes after parenteral administration and 1-2 hours after oral administration
High-Yield Explanation
Ref: Goodman and Gilman 12th/506-507 Methadone *The onset of analgesia occurs 10-20 minutes after parenteral administration of methadone and 30-60 minutes after oral administration. *It is well absorbed from the GI tract and can be detected in plasma within 30 minutes of oral ingestion. *Primary uses are relief of chronic pain and in main tenance therapy of opioid addiction.

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