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Pharmacology Anti Histaminics ee097bda

About cetirizine all are true except-

A
It is a 2nd generation anti histaminic
B
It is a metabolite of hydroxyzine
C
Good CNS penetration
D
Inhibits release of histamine
High-Yield Explanation
Ans. is 'c' i.e., Good CNS penetration Cetrizine* Cetrizine is a 2nd generation anti histaminic* It is a metabolite of hydroxyzine with marked affinity for the peripheral H1 receptors,* It penetrates CNS poorly and has mild sedating effect.* It inhibits release of histamine from mast cells and therefore has been used for urticarial and atopic dermatitis.* It is non - arrhythmogenic.

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