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A case of hepatocellular carcinoma involving segment IV and VI without any metastasis in a 62 year old alcoholic may be treated by all of the following except -

A
Total hepatectomy and liver transplant
B
Radiation therapy
C
Chemoembolization
D
Cryotherapy
High-Yield Explanation
Ans. is 'd' i.e., Cryotherapy o There are large number of treatment options for patients with hepatocellular carcinoma:# The only t/t modality with curative potential is- "Complete excision of hepatocellular carcinoma either by partial hepatectomy or by total hepatectomy and transplant"# Radiofrequency ablation and surgical resection have been equally effective for potentially resectable hepatocellular carcinoma in some studies so some consider radiofrequency ablation as potentially curative.T/t options for hepatocellular carcinoma :a) Surgicalc) Transarterial# Resection# Orthotopic liver transplant# Embolization# Chemoembolization# Radiotherapyb) Ablative# Percutaneous ethanol injection# Percutaneous acetic acid injection# Thermal ablation (cryotherapy, radiofrequency ablation, microwave)d) Combination transarterial/ablativee) External beam radiationf) Systemic# Chemotherapy# Hormonal therapy# Immunotherapy

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