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Pathology Hematology 7425a470

VWF factor deficiency causes:

A
| Platelet adhesion
B
| Factor VIII in plasma
C
Defective platelet adhesion
D
All of the above
High-Yield Explanation
Deficiency of Von willebrand factor (VWF -promote platelet adherence and activation) causes | Platelet adhesion ( |BT ) | Intrinsic pathway activity ( | aPTT) | Factor VIII in plasma C/F Mucosal bleeding - Petechiae /purpura /epistaxis / melena Tissue bleeding Rx - Desmopressin for mild form - Cryoprecipitate for severe form

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