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Pathology Cellular Pathology d1b85a06

Which of the following helps in movement and adhesion?

A
MCP1
B
PGE2
C
LTB4
D
CD31
High-Yield Explanation
Ans. is 'd' i.e., CD31 o Platelet endothelial cell adhesion molecule (PECAM or CD-31) is present on both endothelium and leukocytes. It is the major adhesive molecule for diapedisis.Endothelial - Leukocyte Adhesion MoleculesEndothelial moleculeLeucocyte MoleculeMajor RoleP-selectinSialyl-Lewis X-modified proteinsRollingE-selectinSialyl-Lewis X-modified proteinsRolling and adhesionGlyCam-l,CD34L-selectinRollingICAM-1 (Immunoglobulin family)CD 11/CD 18 2 integrin (LFA-1, Mac-1)Adhesion,arrest, transmigrationVCAM-1 (Immunoglobulin family)VLA-4-1 integrinAdhesionPE CAM-1 (CD-31)PECAM-1 (CD-31)Diapedesis (transmigration)

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