True about iron deficiency anemia – a) Microcytic hypochromic anemiab) Decreased TIBCc) Increased ferritind) Bone marrow iron decreased earlier than serum iron

Characteristics of anemia of iron deficiency Blood picture Microcytic                                o Ring / pessary cells          o Target cells (unusual) Hypochromic                          o Poikilocytosis one marrow Hypercellular marrow            o Erythroid hyperplasia o Depleted bone marrow iron Parameters S. Ferritin                                  -->           Reduced                o Serum transferrin receptors            Increased S. iron                                        -->           Reduced                o Red cell protoporphyrin           --> Increased Total iron binding capacity  —>         Increased                o Hepcidin level               -->                  Increased Percentage saturation            --->          Decreased- In iron deficiency anemia, bone marrow iron decreases earliar than serum iron.