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Pharmacology All India exam cd443fdd

Latest oral direct thrombin inhibitor is?

A
Ximelagatran
B
Indraparinux
C
Dabigatran
D
Fondaparinux
High-Yield Explanation
Ximelagatran was the first oral direct thrombin inhibitor approved; however, it was subsequently withdrawn from the market because of repos of liver failure. Recently a new oral direct inhibitor, dabigatran, was approved for use in Europe for prevention of various thromboembolism in patients who have undergone hip or knee replacement surgery. REF : katzung pharmacology : 14th ed

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