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Physiology G.I.T. c9ea1452

Which of the following is a cholagogne-

A
Secretin
B
CCK
C
VIP
D
Gastrin
High-Yield Explanation
Ans. is 'b' i.e., CCK Regulation of biliary secretion* The entry of bile into the duodenum increases either when the liver cells increase their bile secretion or when the gall bladder pours out its stored bile.1) Cholerectics:# Substances that increase hepatic bile secretion are called cholerectics.# The most importantcholerectics are bile salts themselves. Other cholerectic is secretin.2) Cholagogues:# Substances that cause gall bladder contraction to pour its bile are called cholagogues.# The most important cholagogue is cholecystokinin (CCK). Fatty acids and amino acids in the duodenum stimulate the release of CCK which causes gall bladder contraction.

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