A male 45 years old complains of weakness. He is obese and a type 2 diabetic and hypertensive. General examination reveals hepatomegaly. Icterus is visible on sclera and pale coloration of skin present.Which of the following liver diseases can be seen in this patient?
High-Yield Explanation
For a variety of reasons, lipid—mainly as triacylglycerol—can accumulate in the liver. Extensive accumulation is regarded as a pathologic condition. Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide.
NAFLD is considered by many to be the hepatic manifestation of the ‘metabolic syndrome, as it is strongly associated with obesity, dyslipidaemia, type 2 diabetes and hypertension.
Alcoholic fatty liver disease (AFLD) usually presents with elevated transaminases in the absence of hepatomegaly.
Reference: HARPERS ILLUSTRATED BIOCHEMISTRY30th ed Page no 260,261: Davidson Medicine 23rd edition page no 882