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Pathology General bfa2d49d

Wilson's disease is characterized by ?

A
Increased serum ceruloplasmin
B
Decreased copper excretion in urine
C
Increased copper in liver
D
Autosomal dominant
High-Yield Explanation
Ans. is 'c' i.e., Increased copper in liver Diagnosis of Wilson disease The gold standard for diagnosis is liver biopsy with quantitative copper assay - concentration of copper in a liver biopsy sample > 200 mg/g dry weight. Other tests are ? Serum ceruloplasmin level - low Urine copper excretion - increased KF rings DNA Haplotype analysis.

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