Full 2L QBank
Microbiology General bde9c7d0

Epstein-Barr virus causes autoimmunity by:

A
Molecular mimicry
B
Inducing inappropriate expression of class H MHC
C
Release of sequestere antigens
D
Polyclonal B cell activation
High-Yield Explanation
Ans. (d) Polyclonal B-cell activation EBV receptor (CD-21) on the surface of B-cells is also the receptor for the C3d component of complement. So, when B-cells are infected with EBV they become transformed and can proliferate indefinitely. This polyclonal activation of B-cells leads to the production of antibodies directed against host cells and viral proteins. Thus, this is also not difficult to understand that cellular immunity is more impoant than humoral immunity in controlling EBV infection.

Related Microbiology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now