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Surgery General b36237e5

Not true about polycystic kidney disease is -

A
Autosomal dominant
B
Proteinuria <2gm/day
C
Leads to CRF
D
Decompression of cyst leads to normal renal function
High-Yield Explanation
Decompression or uncapping of cysts (Rovsings operation) is of no use in preserving the renal function. Polycystic kidney disease Is of 2 types: Adult PKD Inheritance is AD Disease manifests itself in adult life. Infantile PKD  Inheritance is AR Disease manifests in infancy as severe renal failure and life expectancy is short. Adult PKD Almost always bilateral (95%) Disease ordinarily does not manifest itself before 40 yr of age. Pts. of APKD have increased frequency of cysts in liver (30%), Pancreas, Spleen"; ovaries & berry aneurysm of cerebral arteries. Pathology - the kidney is enlarged 3 to 4 times. It is studded all over with cysts. Cysts are distributed evenly throughout the cortex & medulla. Content of the cyst varies but its not urine. Renal tissue is progressively replaced by cysts leading to CRF. Clinical Presentation Mass Pain Hypertension (70 to 80% of cases) Henzaturia Infection Uremia Urine examination high output of urine, low specific gravity. It may contain traces of albumin It ultimately leads to CRF and renal transplantation is the only definite t/t.

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