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Pharmacology General 789c69cb

Oral contraceptive failure may be seen with ?

A
Rifampicin
B
Cimetidine
C
Propranolol
D
Ethambutol
High-Yield Explanation
Ans. is 'a' i.e., Rifampicin o Contraceptive failure may occur if the following drugs are given concurrently : (a) Enzyme inducer --> Enhances the metabolism of estrogen & progesterone. Phenytoin 3. Carbamazepine 5. Primidone Phenobarbitone 4. Rifampicin 6. Griseofulvin (b) Suppression of intestinal microflora enterohepatic circulation. 1. Tetracyclines 2. Ampicillin

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