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Pathology General a9472e3d

The intrinsic apoptotic pathway is located in which of the following cellular organelle?

A
Endoplasmic reticulum
B
Golgi apparatus
C
Mitochondria
D
Cell membrane
High-Yield Explanation
Mitochondria are remarkable organelles in that they contain proteins such as cytochrome c that are essential for life, but some of the same proteins, when released into the cytoplasm (an indication that the cell is not healthy), initiates the suicide program of apoptosis. Ref: Robbins 8th edition, Chapter 1

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