Premature ovarian insufficiency is defined as hypogonadotropic hypogonadism and amenorrhea arising before the age of
High-Yield Explanation
Premature ovarian failure (POF), traditionally defined as hypogonadotropic hypogonadism and amenorrhea arising before the age of 40.Reference: Clinical gynecologic endocrinology; 10th edition; Chapter 9; Normal and Abnormal Sexual Development; Page no: 463