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Biochemistry Lipids a66f6340

Niemann-Pick disease is characterized by:

A
Increased concentration of sphingomyelin in liver
B
Increased concentration of cerebrosides in liver and spleen.
C
Increased concentration of plasminogen
D
Increased accumulation of glycerol in liver
High-Yield Explanation
Ans. A. Increased concentration of sphingomyelin in liverNiemann -pick disease is due to the absence of sphingomyelinase enzyme which leads to the accumulation of sphingolipids or sphingomyelin in liver.

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