Stage- II testicular teratoma is treated by-
High-Yield Explanation
• Most common testicular tumor in prepubertal adults: Teratoma
• Tumor is composed of two or more embryonic germ cell layers that may be both mature and immature.
• Tumor is very heterogeneous with both solid and cystic components.
Teratoma is divided into three subsets
1. Mature: well-differentiated ectodermal, mesodermal, or endodermal tissues
2. Immature: incompletely differentiated tissues
3. Teratoma with areas of malignant transformation: sarcoma, squamous carcinoma, adenocarcinoma
• Teratomas are potentially malignant
Clinical Features
• Age range: first, second, and third decades.
• Mature and immature forms have metastatic potential in adults but in children are uniformly benign.
• The primary tumor generally presents as an enlarged testis with both solid and cystic components.
• The teratoma component of metastatic GCT is resistant to chemotherapy and radiotherapy.
Tumor Markers
• AFP is raised in 20-25%