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Pharmacology Chemotherapy a567c0ca

Sustained neutropenia is seen with?

A
Vinblastine
B
Cisplatin
C
Carmustine
D
Cyclophosphamide
High-Yield Explanation
Carmustine belongs to the group of alkylating agents. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by carmustine, other effects may occur. Carmustine injection is used alone or together with other medicines to treat ceain type of brain tumors (e.g., glioblastoma, brainstem glioma, medulloblastoma, astrocytoma, ependymoma, and metastatic brain tumors), cancer of the lymph system (e.g., Hodgkin&;s disease, non-Hodgkin&;s lymphoma), and a ceain type of cancer in the bone marrow (e.g., multiple myeloma). Marked neutropenia is frequently observed following administration of this drug REFERENCE: www.mayoclinic.org

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