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Pharmacology Prostaglandins a45c1748

Mechanism of action of zileuton:

A
Inhibit prostaglandin synthesis
B
Inhibit COX
C
Inhibit LOX
D
Inhibit mast cells
High-Yield Explanation
Ans. C. Inhibit LOXArachidonic acid is acted upon by two enzyme-COX and LOX. Lox converts it into leukotrienes and Cox into prostaglandin. Zileuton is the inhibitor of LOX enzyme and it is used in treatment of asthma.

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