Most effective natural barrier to rabies -

<p> RABIES:- Rabies, an acute highly fatal viral disease of CNS caused by Lyssavirus type 1( neurotropic RNA virus). Mode of transmission- Deep bite/ scratch by an infected animal. Dogs are the main host and transmitter if rabies. Transmission can also occur when infectious material usually saliva comes into direct contact with human mucosa/fresh skin wounds. Humam to human transmission even though possible yet not confirmed. Rabies can be contracted by inhalation of virus containing aerosols / transplantation of an infected organ. Ingesting raw meat/ other tissues from animals infected with rabies is not a source of infection. Water appears to be the most effective natural barrier to rabies. {Reference: park&;s textbook of preventive and social medicine, 23rd edition, pg no.277}</p>