Long-term use of which of the following diuretic agent results in gynaecomastia?
High-Yield Explanation
Potassium-sparing diuretics may produce hyperkalemia, paicularly in patients with renal insufficiency and those taking ACE inhibitors or angiotensin receptor blockers; Spironolactone is associated with gynecomastia- as it inhibits aldosterone Reference: Katzung Pharmacology; 13th edition; Chapter 11; Antihypeensive Agents