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Gynaecology & Obstetrics Abortion 8869fa56

A woman with H/o recurrent abortions presents with isolated increase in APTT. Most likely cause is:

A
Lupus anticoagulant
B
Factor VII
C
Von Willebrand's disease
D
Hemophilia A
High-Yield Explanation
Ans. is a, i.e. Lupus anticoagulantRef. Dutta Obs. 6/e, p 343; Fernando Arias 3/e, p 327; Leon Speroff 7/e, p 1082Isolated increase in APTT is suggestive of lupus anticoagulant.

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