Vasculitis involving the Aoic arch is

Takayasu aeritis classically involves the aoic arch. This is a granulomatous vasculitis of medium and larger aeries characterized principally by ocular disturbances and marked weakening of the pulses in the upper extremities (hence the name pulseless disease). Takayasu aeritismanifests with transmural fibrous thickening of the aoa-- paicularly the aoic arch and great vessels--with severe luminal narrowing of the major branch vessels.Ref: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Chapter 11; Blood vessels; Page no: 508