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Biochemistry Basics of DNA 80d1164b

At physiologic pH, DNA is

A
Positively charged
B
Negatively charged
C
Amphoteric
D
Uncharged
High-Yield Explanation
Nucleic acid carries negative charge at physiological pH Negative charge at physiologic pH is due to presence of phosphodiester linkages This propey is useful for the separation of DNA or RNA by electrophoresis. DNA will move towards the anode. Shoer DNA molecules will move faster than longer molecules in agarose gel electrophoresis.

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