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Medicine Respiratory 395d0130

Proximal bronchiectasis, blood eosinophilia and asthma are characteristic feature of

A
Histoplasmosis
B
Measles
C
Allergic bronchopulmonary aspergillosis
D
Tuberculosis
High-Yield Explanation
Ans. c (Allergic bronchopulmonary aspergillosis). (Ref. Harrison, Medicine, 16th ed., 1178, 1488 Table 237-3)Diagnostic features of allergic bronchopulmonary aspergillosis (ABPA)Main diagnostic criteriaOther diagnostic featuresBronchial asthmaPulmonary infiltratesPeripheral eosinophilia (>1000/ mL)Immediate wheal-and-flare response to A. fumigatusSerum precipitins to A. fumigatusElevated serum IgECentral bronchiectasisHistory of brownish plugs in sputumCulture of A. fumigatus from sputumElevated IgE (and IgG) class antibodies specific for A.fumigatus.

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