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Pharmacology General 7b84d3bc

Antiinflammatory action of steroid is due to inhibition of

A
Cyclooygenase
B
Lipooxygenase
C
Phospholipase A2
D
Myeloperoxidase
High-Yield Explanation
Ans. is'c' i.e., Phospholipase A2(Ref: KDT Vh/e p. 286)Glucocoicoids interfere at several steps in the inflammatory response but the most impoant overall mechanism appears to be limitation of recruitment of inflammatory cells at the local site and production of proinflammatory mediators like PCs. LTs. PAF through inhibition of phospholipase A2

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