Which of the following statement is TRUE about iron response element?
High-Yield Explanation
mRNAs of ferritin and tfR 1 contain a stem-loop structure known as Iron Response Element (IRE). IRE of ferritin mRNA is located at its 5' UTR. (Ferritin ->Five) - option c is wrong IRE of transferrin receptor is located at its 3'UTR. (TfR ->Three) - option b s wrong. IRP-IRE interaction prevents the translation of ferritin mRNA. IRP-IRE interaction stabilises the mRNA of transferrin receptor-more intracellular iron absorption.- option d is wrong.