Pathology Misc. (W.B.C) 7a9b884e MYD88 L265P mutation is seen in? A Hairy cell leukemia B Waldenstrom Macroglobulinemia C Multiple Myeloma D AML High-Yield Explanation Ans. (b) Waldenstrom MacroglobulinemiaMYD88 (L265P) mutation is detectable in all patients with Waldenstro..m's macroglobulinemia, therefore representing a hallmark of the disease.