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Pathology Urinary tract 56c7f067

Kimmelsteil -Wilson lesions in kidney consists of-

A
Splitting of glomerular basement membrane
B
Nodular sclerosis of the glomeruli
C
Hyaline sclerosis
D
Hyperplastic aeriosclerosis
High-Yield Explanation
Nodular lesions of diabetic glomerulosclerosis are also called as Kimmelstiel-Wilson (KW) lesions or intercapillary glomerulosclerosis.These lesions are specific for type 1 diabetes (juvenile onset diabetes) or islet cell antibody-positive diabetes mellitus. The pathologic changes consist of one or more nodules in a few or many glomeruli. A nodule is an ovoid or spherical, laminated, hyaline, acellular mass located within a lobule of the glomerulus. The nodules are surrounded peripherally by glomerular capillary loopswhich may have normal or thickened GBM Ref: Harsh Mohan textbook of pathology page 678 6th edition Repeated question.

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