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Surgery General 60eb0fca

Cholesterosis is -

A
Disease of defective metabolism of choline
B
Concerned with epithelial tumours of brain
C
Diffuse depositon of cholesterol in mucosa of gall bladder
D
Disease concerned with obstructive jaunidce
High-Yield Explanation
• It is an acquired histologic abnormality of the gallbladder epithelium that results in an excessive accumulation of lipid (cholesterols esters and triglyceride)Q within epithelial macrophage of the GB wall. • Cholesterol stones are found in half of the cases. Pathology • Gross Appearance: The mucosa has pale, yellow streaks running longitudinally giving rise to the term strawberry gallbladder (although the mucosa is usually bile stained rather than red). • Diffuse form (“strawberry gallbladder”): GB mucosa is brick red and speckled with bright yellow flecks of lipid. • Localized form: Solitary or multiple “cholesterol polyps” studding the gallbladder wall. Treatment • Cholecystectomy is indicated in symptomatic cholesterolosis or when cholelithiasis is present.

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