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Surgery General 2c1f1895

True of autosomal dominant polycystic kidney disease I and II respectiely -

A
Chromosomes 16 and 5
B
16 and 4
C
11 and 5
D
11 and 4
High-Yield Explanation
Answer is 'b' i.e. 16 and 4 Three forms of ADPKD have been identified. ADPKD-1 - accounts for 85% of cases - its gene is found on chromosome 16p ADPKD-2 - its gene has been mapped to chromosome 4q - it appears to have a later age of onset of symptoms and renal failure than ADPKD-1 ADPKD-3 - it has not been mapped to a gene uptill now.

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