Chromosome inversion is:

Inversion: Occur when there are two interstitial of a single chromosome breaks in and the segment reunites & rearranged after a complete turnaround. Option A - Deletion e.g. Wolf-Hirschhorn syndrome, Jacobsen syndrome, also called the terminal IIq deletion disorder. Option B - Duplication - e.g. Charcot-Marie-Tooth disease type 1A Option D - Insertion Other structural disorders of chromosomes: Rings: A portion of a chromosome has broken off and formed a circle or ring. This can happen with or without loss of genetic material. Isochromosome: Formed by the mirror image copy of a chromosome segment including the centromere. Aneuploidy: Numerical disorder of chromosomes. Missing a chromosome from a pair is called monosomy and presence of more than two chromosomes of a pair (trisomy, tetrasomy, etc.)