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Pharmacology Central Nervous system 4fcc1724

Which of the following antiepileptic agent does not act Na+ channel modulation?

A
Vigabatrin
B
Phenytoin
C
Valproate
D
Lamotrigne
High-Yield Explanation
it is an inhibitor of GABAtransaminase, the enzyme which degrades GABA. Anticonvulsant action may be due to increase in synaptic GABA concentration REF KD TRIPATHI 8TH ED.

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