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Surgery Breast 49ccabc6

All the statements are true for medullary carcinoma breast except?

A
Associated with BRCA-2.
B
Usually triple negative
C
Axillary lymph node enlargement bacause of reactive hyperplasia
D
Lymphoreticular infiltration
High-Yield Explanation
Medullary carcinoma of breast Invasive breast cancer 5% of breast cancers Associated with BRCA-1 Axillary lymph node enlargement bacause of reactive hyperplasia Lymphoreticular infiltration Electron M/E - Bizarre cells with high-grade nuclear features Syncytial pattern -Sheets of cells surrounded mononuclear lymphocytes. Borders push into the adjoining breast tissue In its pure form, High grade, Triple negative - ER and PR negative,Her-2-neu negative

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