Full 2L QBank
Pharmacology Autacoids 3f8bd29d

Which of the following statement is not true about NSAIDs

A
Acetylsalicylic acid is an Irreversible inhibitors of Cox enzyme acetylsalicylic acid is an Irreversible inhibitors of Cox enzyme
B
Acetylsalicylic acid reduces in Vivo synthesis of prostaglandins
C
Its clearance is independent of Plasma concentration
D
Antiplatelet effect of low dose aspirin is related to pre systemic Cox inhibition
High-Yield Explanation
Acetylsalicylic acid (asprin) is an Irreversible inhibition of COX enzyme. IT results in inhibition of prostaglandin and TX synthesis at low doses for (40 to 325 milligrams) it exes antiplatelet action. this drug shows saturation kinetics at high doses that is kinetics changes from first order to zero order. therefore at high doses amount of drug exeed will be constant that means clearance il is not constant. Refer kDT 6/e p185

Related Pharmacology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now