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Gynaecology & Obstetrics Twin Pregnancy, Molar Pregnancy, Gestational Trophoblastic disease and contraception in special situations (Sour Grapes!) 376175ca

Hypeension, proteinuria, and pitting edema are noted in the second month of the first pregnancy in a 25-year-old woman. The pathogenesis of her presenting complains is most closely associated with:-

A
A benign tumor of the chorionic villi
B
Gestational diabetes mellitus
C
Primary endometrial cancer
D
A malignant trophoblastic tumor
High-Yield Explanation
Features of pre-eclampsia (hypeension, proteinuria, pitting edema) in the first trimester is most often secondary to a hydatidiform mole, which is a benign neoplasm of the chorionic villi. The uterus is frequently larger than the gestational age, Fetal Pas are not felt. Choricarcinomas are malignant trophoblastic tumors that most commonly develop from a preexisting complete mole,in 50% of cases although they can also be seen following a Normal pregnancy and aboion in 25% cases each

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