Which of the following disorders is least likely associated with progression to lymphoma

Ans. is 'c' i.e., Severe combined immunodeficiency Choice Cancers associated Sjogren syndrome NHL mainly MALT-oma involving salivary glands>stomach Ataxia telengectasia Elevated incidence of cancers, approximately 100-fold in comparison to the general population. In children, more than 85% of neoplasm cases are acute lymphocytic leukemia or lymphoma. In adults with ataxia-telangiectaisa, solid tumors are more frequent Lynch-II syndrome Gastrointestinal cancer associated with endometrial/ovarian carcinoma. Early onset brain tumor and lymphoma also seen in children